Wonderfull Treat

In the morning, apply a treatment serum that contains antioxidants like vitamins C and E and a moisturizer that contains a humectant, like hyaluronic acid or glycerin. 

Antioxidants fight free radicals, the molecules that damage the DNA in healthy skin cells, and have been shown to encourage collagen production. They also help mitigate the damage from UVA and UVB rays and reduce the appearance of dark spots, says Fusco. Look for a formula that contains ascorbic acid (vitamin C) and comes in an airtight pump or tube. For best results, use a mix of antioxidants, says Cheryl Karcher, MD, a New York City dermatologist; for instance, you could apply a serum that contains vitamins C and E in the A.M., and a lotion with an antioxidant such as selenium, zinc or green tea in the evening.

Hyaluronic and glycerin are two of the best ingredients for drawing moisture into the skin. Moisturizing is key because it helps support the skin barrier, which can be compromised by cold air, dry heat and other environmental insults. When the skin barrier is compromised, you're more vulnerable to irritation and infection, says Gohara. Keeping your skin well hydrated also temporarily plumps it up, diminishing fine lines and wrinkles.
For nighttime, the gold standard treatment is a retinoid, the vitamin A derivative that's been shown to increase collagen production, regenerate elastin, unclog pores (reducing their appearance) and stimulate cell turnover (helping eliminate dark spots). Great news: There are many formulations of prescription retinoids and their over-the-counter versions, retinols, so it's much easier than it used to be to find one that doesn't irritate, says Fusco. If you've never tried one (or if you have sensitive skin), start with an over-the-counter retinol; it will be less potent than a prescription and not as likely to cause redness and flaking.  Use that twice a week and build up tolerance until you can use it every night. Then you can graduate to a cosmeceutical strength (just below prescription strength), says Fusco, following the same routine. (Fusco recommends If your skin tolerates that, you can move on to a prescription retinoid (such as ReFissa or a generic tretinoin). 

What goes on first? Apply products according to their consistency, beginning with the thinnest. In the morning, start with the treatment serum, then follow it with a lotion or a cream moisturizer. For combination or oily skin, begin with a vitamin C serum (try Over that, layer a moisturizing lotion or gel (we like . For mature or very dry skin, start with a vitamin C or hyaluronic acid serum (such as ) and follow it with a lotion or cream containing glycerin. You can seal in the moisture by patting a face oil over that, says Fusco. is a good one.)